The Axe makes a brief appearance in Call of Duty: Black Ops II. It is only featured once on the campaign level Time and Fate during the part when Raul Menendez is playable. Near the beginning of the level, the player must go up a hill and through a small shack. The axe is inside of the shack, and the pick-up text "Use" appears when reaching it. The player can only use it before the PDF soldiers holding the five civilians captive notice them. If they pick it up, the axe will automatically be thrown to the left-most soldier. They cannot pick it up again after using it or being noticed.
On the map Fog from the Onslaught DLC pack, upon obtaining the Michael Myers Field Order reward, the player is given the weapon to use. It is a one-hit-kill, and victims' "souls" expel out of their bodies upon death. Melee actions with the axe are at an increased speed from the Combat Knife as seen in Multiplayer.