There are multiple characters in the Call of Duty series with the name Lewis:
- Lewis (Call of Duty) - An American soldier in the 82nd Airborne Division.
- Lewis (Finest Hour) - An American soldier in Able Company.
- Lewis (Modern Warfare 3: Defiance) - A British SFSG soldier who assists in recapturing an airport under Russian occupation.
- Lewis (weapon) - A light machine gun featured in Call of Duty: WWII.