M2 may refer to:
- M2 Flamethrower - A flamethrower used in Call of Duty: World at War, Call of Duty: World at War (DS), Call of Duty: World at War: Final Fronts and Call of Duty: Black Ops.
- M2 Browning Machine Gun - A mounted machine gun that appears in most games of the series.
- Mk 2 Grenade (also referred to as M2 Grenade) - A fragmentation grenade that appears frequently in the series.
- M2 Mortar - A fixed weapon in Call of Duty: Modern Warfare 3.