Samantha Maxis was born to Ludvig Maxis and his unknown wife. After his wife died, Maxis made sure she was always close to him. Due to his research, however, he neglected her and failed to notice Richtofen's experiments on her. As the experiments went on, Richtofen grew to hate her, perhaps due to Maxis' attachment to her or due to what she had become. When Richtofen trapped Sam in the room with Fluffy and activated the teleporter, she was teleported to Griffin Station. There in a panic she accidentally came in contact with the M.P.D. and took control of the zombies. In an effort to stop her and free her so that Richtofen could operate it, Groph and Schuster found and brought Maxis to her. However, Maxis told her to kill them all and disappeared, sending Samantha over the edge and on a rampage to destroy all of Group 935, which had betrayed Maxis. After Richtofen trades bodies with her to control the zombies, she and the super soldier test subjects activate Maxis's backup plan and incinerate the earth, leaving Richtofen trapped in her body and able to control the Zombies on the Moon and the remaining Zombies on Earth.
In Samantha's demonic room in Kino der Toten, her room features a Teddy Bear and a Monkey Bomb. It also has a crude replica of Der Riese complete with miniatures of the original characters.
She was the Demonic Announcer for all Zombies maps until after Richtofen's Grand Scheme is completed in Moon, at which point she would be replaced by Richtofen.
In a radio found on Moon, it is revealed that her mother is dead.
Like Sarah Michelle Gellar, she recycles male grunting sounds when landing or diving to prone.
According to a message in the Black Ops Data Servers, Samantha is aged around 6 to 10 at the time of her requesting a dog from her father.
She is the first child to have a role in the Call of Duty series.
She is the only playable child in the Call of Duty series.
In the Call of Duty: Modern Warfare 3 mission, "Bag and Drag", there is a reference to Samantha on a wall where the word "Sami" is written and a picture of a girl holding a teddy bear and a hammer.
She reappears in Call of Duty: Black Ops II as the Demonic Announcer in the map Nuketown Zombies. She remains as the announcer until round 25, then Richtofen takes over as the announcer and the zombies eyes turn blue. Due to Richtofen's Grand Scheme happening on Moon at the same time.
Richtofen often references her in Call of Duty: Black Ops II, claiming that she cheated when she was in control of the zombies.
Samantha's voice is reused for the Demonic Announcer in Mob of the Dead, but it is unlikely to be her as it takes place many years before she is sent to the MPD (like in Nacht Der Untoten). The new voice could possibly be the original Demonic Announcer instead, as his voice is heard at the beginning of Grief.
